{"id":123939,"date":"2021-05-06T03:55:07","date_gmt":"2021-05-06T03:55:07","guid":{"rendered":"https:\/\/precoinnews.com\/?p=123939"},"modified":"2021-05-06T03:55:07","modified_gmt":"2021-05-06T03:55:07","slug":"modernas-covid-19-vaccine-booster-shots-effective-against-virus-variants","status":"publish","type":"post","link":"https:\/\/precoinnews.com\/business\/modernas-covid-19-vaccine-booster-shots-effective-against-virus-variants\/","title":{"rendered":"Moderna’s COVID-19 Vaccine Booster Shots Effective Against Virus Variants"},"content":{"rendered":"

Moderna Inc. (MRNA) said initial data from its ongoing phase 2 study showed that booster shots of its COVID-19 vaccine is effective against strains of the coronavirus<\/span> that emerged from Brazil and South Africa. The company is also evaluating a multivalent vaccine booster candidate, mRNA-1273.211, and expects to share its data shortly.<\/p>\n

The biotechnology company said initial data from its phase 2 study showed that a single 50 \u00b5g dose of mRNA-1273 or mRNA-1273.351 given as a booster to previously vaccinated clinical trial participants increased neutralizing antibody titer responses against SARS-CoV-2 and two variants of concern, the B.1.351 (first identified in the Republic of South Africa) and the P.1 (first identified in Brazil).<\/p>\n

A booster dose of mRNA-1273.351 achieved higher neutralizing antibody titers against the South Africa variant of concern than a booster dose of mRNA-1273.<\/p>\n

The safety and tolerability profiles following third dose booster injections of 50 \u00b5g of mRNA-1273 or mRNA-1273.351 were generally comparable to those observed after the second dose of mRNA-1273 in the previously reported Phase 2 and Phase 3 studies. The majority of adverse events were mild or moderate in severity. <\/p>\n

In the ongoing phase 2 study, three strategies for boosting neutralizing titers in previously vaccinated participants are being evaluated: mRNA-1273.351, a booster candidate based on the South African variant; mRNA-1273.211, a multivalent booster candidate which combines a 50-50 mix of mRNA-1273, Moderna’s authorized vaccine against ancestral strains and mRNA-1273.351 in a single vaccine, and a 50 \u00b5g booster dose of mRNA-1273.<\/p>\n

The update includes preliminary data two weeks following administration of a booster dose of mRNA-1273 or mRNA-1273.351. Evaluation of additional samples collected at later timepoints after the booster, the company’s multivalent vaccine candidate, mRNA-1273.211, and a lower dose of mRNA-1273.351 are ongoing and data is expected shortly.<\/p>\n

Moderna COVID-19 Vaccine is authorized for use under an Emergency Use Authorization for active immunization to prevent COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 18 years of age and older. <\/p>\n

Source: Read Full Article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Moderna Inc. (MRNA) said initial data from<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23051],"tags":[],"yoast_head":"\nModerna's COVID-19 Vaccine Booster Shots Effective Against Virus Variants - Pre Coin News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/precoinnews.com\/business\/modernas-covid-19-vaccine-booster-shots-effective-against-virus-variants\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Moderna's COVID-19 Vaccine Booster Shots Effective Against Virus Variants - Pre Coin News\" \/>\n<meta property=\"og:description\" content=\"Moderna Inc. 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